sucD protein (Myxococcus xanthus) - STRING interaction network

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sucD

succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (299 aa)

Predicted Functional Partners:

sucC

0.999

sdhB

0.994

sdhA

0.992

sdhC

0.983

frdB

0.977

frdA

0.973

sucB

0.968

sucA

0.955

mutB

0.942

mutA

0.942

Your Current Organism:

Myxococcus xanthus

NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
frdA	frdB	MXAN_5224	MXAN_5222	Fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811.	Fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM PF00037.	0.999
frdA	sdhA	MXAN_5224	MXAN_3539	Fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811.	Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to SP:P08065; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01811.	0.912
frdA	sdhB	MXAN_5224	MXAN_3540	Fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811.	Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:P08066; match to protein family HMM PF00037; match to protein family HMM TIGR00384.	0.993
frdA	sdhC	MXAN_5224	MXAN_1072	Fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811.	Succinate dehydrogenase cytochrome b558 subunit; Identified by similarity to SP:P08064.	0.997
frdA	sucA	MXAN_5224	MXAN_6035	Fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811.	2-oxoglutarate dehydrogenase, E1 component; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239.	0.806
frdA	sucB	MXAN_5224	MXAN_6036	Fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.590
frdA	sucC	MXAN_5224	MXAN_3541	Fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811.	succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.974
frdA	sucD	MXAN_5224	MXAN_3542	Fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811.	succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.973
frdB	frdA	MXAN_5222	MXAN_5224	Fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM PF00037.	Fumarate reductase, flavoprotein subunit; Identified by similarity to GB:AAO42600.1; match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01811.	0.999
frdB	sdhA	MXAN_5222	MXAN_3539	Fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM PF00037.	Succinate dehydrogenase, flavoprotein subunit; Identified by similarity to SP:P08065; match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01811.	0.996
frdB	sdhB	MXAN_5222	MXAN_3540	Fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM PF00037.	Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:P08066; match to protein family HMM PF00037; match to protein family HMM TIGR00384.	0.900
frdB	sdhC	MXAN_5222	MXAN_1072	Fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM PF00037.	Succinate dehydrogenase cytochrome b558 subunit; Identified by similarity to SP:P08064.	0.997
frdB	sucA	MXAN_5222	MXAN_6035	Fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM PF00037.	2-oxoglutarate dehydrogenase, E1 component; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239.	0.772
frdB	sucB	MXAN_5222	MXAN_6036	Fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM PF00037.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.622
frdB	sucC	MXAN_5222	MXAN_3541	Fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM PF00037.	succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.971
frdB	sucD	MXAN_5222	MXAN_3542	Fumarate reductase, iron-sulfur protein; Identified by match to protein family HMM PF00037.	succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.977
mutA	mutB	MXAN_2264	MXAN_2263	methylmalonyl-CoA mutase, beta subunit; Identified by similarity to SP:Q05064; match to protein family HMM PF01642.	methylmalonyl-CoA mutase, alpha subunit; Identified by similarity to SP:Q05065; match to protein family HMM PF01642; match to protein family HMM PF02310; match to protein family HMM TIGR00640; match to protein family HMM TIGR00641.	0.999
mutA	sucB	MXAN_2264	MXAN_6036	methylmalonyl-CoA mutase, beta subunit; Identified by similarity to SP:Q05064; match to protein family HMM PF01642.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.825
mutA	sucC	MXAN_2264	MXAN_3541	methylmalonyl-CoA mutase, beta subunit; Identified by similarity to SP:Q05064; match to protein family HMM PF01642.	succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.936
mutA	sucD	MXAN_2264	MXAN_3542	methylmalonyl-CoA mutase, beta subunit; Identified by similarity to SP:Q05064; match to protein family HMM PF01642.	succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.942

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