Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_3598DNA-cytosine methyltransferase; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (505 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.936
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.908
vsr
Very short patch repair protein; Identified by similarity to SP:P09184; match to protein family HMM PF03852.
 
   
 0.903
MXAN_5705
Amidohydrolase domain protein; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.
   
 
  0.903
MXAN_3602
Conserved hypothetical protein; Identified by similarity to GB:BAC15296.1.
 
  
 0.827
MXAN_3603
Conserved hypothetical protein.
 
     0.751
MXAN_3601
ATPase; Identified by match to protein family HMM PF02518.
 
  
 0.749
MXAN_3604
Conserved hypothetical protein; Identified by similarity to GB:BAC12133.1.
 
   
 0.704
hisIE
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Identified by similarity to SP:P06989; match to protein family HMM PF01502; match to protein family HMM PF01503; In the N-terminal section; belongs to the PRA-CH family.
   
    0.536
MXAN_0787
Helicase, DEAD/DEAH family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF01230; match to protein family HMM PF04851; Belongs to the peptidase S24 family.
     
 0.474
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
Server load: medium (50%) [HD]