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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
poxB-2Pyruvate dehydrogenase; Identified by similarity to SP:P07003; match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family. (597 aa)    
Predicted Functional Partners:
MXAN_1282
Putative 3-isopropylmalate dehydratase, large subunit; Identified by match to protein family HMM PF00330; match to protein family HMM PF00694; match to protein family HMM TIGR02087.
 
 
 0.969
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.919
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
  
 0.916
pyk-2
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
  
 0.916
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
 0.914
pdhA
Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.913
pdhB
Pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.913
ldhA
D-lactate dehydrogenase; Identified by similarity to SP:P52643; match to protein family HMM PF00389; match to protein family HMM PF01262; match to protein family HMM PF02826; match to protein family HMM PF03446; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.912
MXAN_0625
Aldehyde dehydrogenase; Identified by similarity to SP:P12693; match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
 0.910
MXAN_0626
Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
 0.910
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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