hemB protein (Myxococcus xanthus) - STRING interaction network

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Score

hemB

Porphobilinogen synthase; Identified by similarity to SP:P30950; match to protein family HMM PF00490; Belongs to the ALAD family. (335 aa)

Predicted Functional Partners:

hemC

0.995

hemL

0.991

hemD

0.953

cobA

0.924

MXAN_3640

0.907

hemA

0.875

hemH

0.779

hemE

0.737

MXAN_2339

0.726

atpD

0.718

Your Current Organism:

Myxococcus xanthus

NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MXAN_2339	cobA	MXAN_2339	MXAN_2338	Siroheme synthase N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	0.999
MXAN_2339	hemA	MXAN_2339	MXAN_2655	Siroheme synthase N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.587
MXAN_2339	hemB	MXAN_2339	MXAN_4100	Siroheme synthase N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	Porphobilinogen synthase; Identified by similarity to SP:P30950; match to protein family HMM PF00490; Belongs to the ALAD family.	0.726
MXAN_2339	hemC	MXAN_2339	MXAN_2656	Siroheme synthase N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.905
MXAN_2339	hemD	MXAN_2339	MXAN_2657	Siroheme synthase N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.699
MXAN_2339	hemL	MXAN_2339	MXAN_0395	Siroheme synthase N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by similarity to SP:P48247; match to protein family HMM PF00202; match to protein family HMM TIGR00713.	0.783
MXAN_3640	cobA	MXAN_3640	MXAN_2338	Siderophore biosynthesis aminotransferase; Assignment partially based on genome context in siderophore gene cluster; identified by similarity to GB:AAG31135.1; match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	0.551
MXAN_3640	hemA	MXAN_3640	MXAN_2655	Siderophore biosynthesis aminotransferase; Assignment partially based on genome context in siderophore gene cluster; identified by similarity to GB:AAG31135.1; match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.863
MXAN_3640	hemB	MXAN_3640	MXAN_4100	Siderophore biosynthesis aminotransferase; Assignment partially based on genome context in siderophore gene cluster; identified by similarity to GB:AAG31135.1; match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Porphobilinogen synthase; Identified by similarity to SP:P30950; match to protein family HMM PF00490; Belongs to the ALAD family.	0.907
MXAN_3640	hemC	MXAN_3640	MXAN_2656	Siderophore biosynthesis aminotransferase; Assignment partially based on genome context in siderophore gene cluster; identified by similarity to GB:AAG31135.1; match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.901
MXAN_3640	hemD	MXAN_3640	MXAN_2657	Siderophore biosynthesis aminotransferase; Assignment partially based on genome context in siderophore gene cluster; identified by similarity to GB:AAG31135.1; match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.700
MXAN_3640	hemE	MXAN_3640	MXAN_5373	Siderophore biosynthesis aminotransferase; Assignment partially based on genome context in siderophore gene cluster; identified by similarity to GB:AAG31135.1; match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.450
atpD	hemB	MXAN_6923	MXAN_4100	ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.	Porphobilinogen synthase; Identified by similarity to SP:P30950; match to protein family HMM PF00490; Belongs to the ALAD family.	0.718
cobA	MXAN_2339	MXAN_2338	MXAN_2339	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	Siroheme synthase N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	0.999
cobA	MXAN_3640	MXAN_2338	MXAN_3640	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	Siderophore biosynthesis aminotransferase; Assignment partially based on genome context in siderophore gene cluster; identified by similarity to GB:AAG31135.1; match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.551
cobA	hemA	MXAN_2338	MXAN_2655	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.844
cobA	hemB	MXAN_2338	MXAN_4100	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	Porphobilinogen synthase; Identified by similarity to SP:P30950; match to protein family HMM PF00490; Belongs to the ALAD family.	0.924
cobA	hemC	MXAN_2338	MXAN_2656	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.992
cobA	hemD	MXAN_2338	MXAN_2657	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.998
cobA	hemE	MXAN_2338	MXAN_5373	uroporphyrin-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.935