STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_4200Putative macrolide-specific efflux protein MacA; Identified by similarity to SP:P75830; match to protein family HMM PF00529; match to protein family HMM TIGR01730; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (482 aa)    
Predicted Functional Partners:
MXAN_4201
Putative macrolide efflux ABC transporter, permease protein; Identified by similarity to SP:P75831; match to protein family HMM PF02687.
 
 
 0.951
macB
Putative macrolide efflux ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.933
MXAN_0107
Putative ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
 
 0.854
MXAN_4173
Putative ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
 
 0.850
MXAN_4198
Putative outer membrane macrolide efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 
 0.850
MXAN_0108
Putative ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
 
 0.848
MXAN_4172
Putative ABC transporter, permease protein; Identified by match to protein family HMM PF02687.
 
 
 0.847
MXAN_4174
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
 
 
 0.821
MXAN_5168
ABC transporter ATP-binding protein; Identified by match to protein family HMM PF02687.
 
 
 0.793
MXAN_3648
Putative permease; Identified by match to protein family HMM PF02687.
 
 
 0.776
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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