node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MXAN_0278 | MXAN_4217 | MXAN_0278 | MXAN_4217 | Mercuric reductase, truncated; Identified by similarity to SP:P16171; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992. | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | 0.850 |
MXAN_0278 | gcvH | MXAN_0278 | MXAN_3041 | Mercuric reductase, truncated; Identified by similarity to SP:P16171; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.759 |
MXAN_0278 | lipA | MXAN_0278 | MXAN_4218 | Mercuric reductase, truncated; Identified by similarity to SP:P16171; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.536 |
MXAN_0278 | sucB | MXAN_0278 | MXAN_6036 | Mercuric reductase, truncated; Identified by similarity to SP:P16171; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992. | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.827 |
MXAN_4216 | MXAN_4217 | MXAN_4216 | MXAN_4217 | Tetratricopeptide repeat/ClpX C4-type zinc finger protein; Identified by match to protein family HMM PF06689; match to protein family HMM PF07719. | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | 0.702 |
MXAN_4216 | lipA | MXAN_4216 | MXAN_4218 | Tetratricopeptide repeat/ClpX C4-type zinc finger protein; Identified by match to protein family HMM PF06689; match to protein family HMM PF07719. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.556 |
MXAN_4216 | lipB | MXAN_4216 | MXAN_4215 | Tetratricopeptide repeat/ClpX C4-type zinc finger protein; Identified by match to protein family HMM PF06689; match to protein family HMM PF07719. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the Nudix hydrolase family. | 0.777 |
MXAN_4217 | MXAN_0278 | MXAN_4217 | MXAN_0278 | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | Mercuric reductase, truncated; Identified by similarity to SP:P16171; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992. | 0.850 |
MXAN_4217 | MXAN_4216 | MXAN_4217 | MXAN_4216 | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | Tetratricopeptide repeat/ClpX C4-type zinc finger protein; Identified by match to protein family HMM PF06689; match to protein family HMM PF07719. | 0.702 |
MXAN_4217 | gcvH | MXAN_4217 | MXAN_3041 | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.599 |
MXAN_4217 | gor | MXAN_4217 | MXAN_2318 | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | Glutathione-disulfide reductase; Maintains high levels of reduced glutathione. | 0.846 |
MXAN_4217 | lipA | MXAN_4217 | MXAN_4218 | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.836 |
MXAN_4217 | lipB | MXAN_4217 | MXAN_4215 | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the Nudix hydrolase family. | 0.883 |
MXAN_4217 | lpdA | MXAN_4217 | MXAN_4219 | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | Alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350. | 0.995 |
MXAN_5057 | lipA | MXAN_5057 | MXAN_4218 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.699 |
fghA | lipA | MXAN_7093 | MXAN_4218 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.692 |
gcvH | MXAN_0278 | MXAN_3041 | MXAN_0278 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Mercuric reductase, truncated; Identified by similarity to SP:P16171; match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992. | 0.759 |
gcvH | MXAN_4217 | MXAN_3041 | MXAN_4217 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Alpha keto acid dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by similarity to GB:CAA37630.1; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | 0.599 |
gcvH | gor | MXAN_3041 | MXAN_2318 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glutathione-disulfide reductase; Maintains high levels of reduced glutathione. | 0.716 |
gcvH | lipA | MXAN_3041 | MXAN_4218 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.945 |