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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nnrDYjeF-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimer [...] (511 aa)    
Predicted Functional Partners:
MXAN_4348
Conserved hypothetical protein TIGR00150; Identified by similarity to GB:AAR35177.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150.
 
 
 0.930
pdxJ
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
     
 0.823
acpS
Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.813
MXAN_5949
Identified by match to protein family HMM PF00753.
  
 0.803
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the Nudix hydrolase family.
  
 0.776
MXAN_3769
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
  
 0.765
MXAN_1246
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
  
 0.762
MXAN_2662
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
  
 0.762
MXAN_4335
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
  
 0.762
MXAN_6513
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
  
 0.762
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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