STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_4393uracil-DNA glycosylase, family 4; Identified by match to protein family HMM PF03167; match to protein family HMM TIGR00758. (186 aa)    
Predicted Functional Partners:
MXAN_3589
Putative uracil-DNA glycosylase, family 4; Identified by match to protein family HMM PF03167.
  
  
0.926
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
      0.699
MXAN_4392
Putative esterase; Identified by match to protein family HMM PF00756.
       0.686
MXAN_5746
M23 peptidase domain protein; Lacks the M23 metal-binding motif and HXH active site. This is characteristic of nonpeptidase members of the M23 family; identified by match to protein family HMM PF01551.
   
   0.602
gpmA
Putative 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
    0.557
MXAN_2559
Peptidase family M22, nonpeptidase-like protein; Identified by match to protein family HMM PF00814.
  
    0.552
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
    
 0.535
MXAN_4004
Conserved hypothetical protein; Identified by similarity to GB:CAD73481.1.
  
     0.510
ssb
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
   0.499
MXAN_4391
Conserved hypothetical protein; Identified by similarity to GB:AAM23984.1.
       0.426
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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