yacG protein (Myxococcus xanthus) - STRING interaction network

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yacG

Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. (97 aa)

Predicted Functional Partners:

gyrA

0.838

MXAN_4427

0.778

MXAN_4426

0.737

gyrB

0.575

MXAN_4429

0.572

MXAN_2485

0.553

MXAN_4430

0.502

MXAN_2483

0.434

MXAN_3604

0.434

MXAN_5971

0.434

Your Current Organism:

Myxococcus xanthus

NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MXAN_2483	MXAN_2485	MXAN_2483	MXAN_2485	Type II DNA topoisomerase, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF01751; match to protein family HMM PF02518.	Type II DNA topoisomerase, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01061; match to protein family HMM TIGR01062; match to protein family HMM TIGR01063.	0.997
MXAN_2483	gyrA	MXAN_2483	MXAN_0766	Type II DNA topoisomerase, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF01751; match to protein family HMM PF02518.	DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.981
MXAN_2483	yacG	MXAN_2483	MXAN_4428	Type II DNA topoisomerase, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF01751; match to protein family HMM PF02518.	Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.	0.434
MXAN_2485	MXAN_2483	MXAN_2485	MXAN_2483	Type II DNA topoisomerase, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01061; match to protein family HMM TIGR01062; match to protein family HMM TIGR01063.	Type II DNA topoisomerase, B subunit; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF01751; match to protein family HMM PF02518.	0.997
MXAN_2485	MXAN_3604	MXAN_2485	MXAN_3604	Type II DNA topoisomerase, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01061; match to protein family HMM TIGR01062; match to protein family HMM TIGR01063.	Conserved hypothetical protein; Identified by similarity to GB:BAC12133.1.	0.805
MXAN_2485	MXAN_5971	MXAN_2485	MXAN_5971	Type II DNA topoisomerase, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01061; match to protein family HMM TIGR01062; match to protein family HMM TIGR01063.	DNA gyrase, B subunit, truncated; Identified by match to protein family HMM PF00204.	0.966
MXAN_2485	gyrB	MXAN_2485	MXAN_0264	Type II DNA topoisomerase, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01061; match to protein family HMM TIGR01062; match to protein family HMM TIGR01063.	DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.967
MXAN_2485	yacG	MXAN_2485	MXAN_4428	Type II DNA topoisomerase, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01061; match to protein family HMM TIGR01062; match to protein family HMM TIGR01063.	Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.	0.553
MXAN_3604	MXAN_2485	MXAN_3604	MXAN_2485	Conserved hypothetical protein; Identified by similarity to GB:BAC12133.1.	Type II DNA topoisomerase, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01061; match to protein family HMM TIGR01062; match to protein family HMM TIGR01063.	0.805
MXAN_3604	gyrA	MXAN_3604	MXAN_0766	Conserved hypothetical protein; Identified by similarity to GB:BAC12133.1.	DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.805
MXAN_3604	yacG	MXAN_3604	MXAN_4428	Conserved hypothetical protein; Identified by similarity to GB:BAC12133.1.	Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.	0.434
MXAN_4426	MXAN_4427	MXAN_4426	MXAN_4427	Putative membrane protein; Identified by match to protein family HMM TIGR00374.	Putative protein-tyrosine phosphatase; Identified by similarity to SP:P39852.	0.769
MXAN_4426	MXAN_4429	MXAN_4426	MXAN_4429	Putative membrane protein; Identified by match to protein family HMM TIGR00374.	NAD(P)H quinone oxidoreductase, PIG3 family; Identified by match to protein family HMM PF00107; match to protein family HMM TIGR02824.	0.544
MXAN_4426	MXAN_4430	MXAN_4426	MXAN_4430	Putative membrane protein; Identified by match to protein family HMM TIGR00374.	Hypothetical protein; Identified by Glimmer2; putative.	0.489
MXAN_4426	yacG	MXAN_4426	MXAN_4428	Putative membrane protein; Identified by match to protein family HMM TIGR00374.	Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.	0.737
MXAN_4427	MXAN_4426	MXAN_4427	MXAN_4426	Putative protein-tyrosine phosphatase; Identified by similarity to SP:P39852.	Putative membrane protein; Identified by match to protein family HMM TIGR00374.	0.769
MXAN_4427	MXAN_4429	MXAN_4427	MXAN_4429	Putative protein-tyrosine phosphatase; Identified by similarity to SP:P39852.	NAD(P)H quinone oxidoreductase, PIG3 family; Identified by match to protein family HMM PF00107; match to protein family HMM TIGR02824.	0.572
MXAN_4427	MXAN_4430	MXAN_4427	MXAN_4430	Putative protein-tyrosine phosphatase; Identified by similarity to SP:P39852.	Hypothetical protein; Identified by Glimmer2; putative.	0.502
MXAN_4427	yacG	MXAN_4427	MXAN_4428	Putative protein-tyrosine phosphatase; Identified by similarity to SP:P39852.	Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.	0.778
MXAN_4429	MXAN_4426	MXAN_4429	MXAN_4426	NAD(P)H quinone oxidoreductase, PIG3 family; Identified by match to protein family HMM PF00107; match to protein family HMM TIGR02824.	Putative membrane protein; Identified by match to protein family HMM TIGR00374.	0.544

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