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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_4825ClpA/B family protein; Identified by similarity to GB:AAC44446.1. (836 aa)    
Predicted Functional Partners:
MXAN_4823
ClpB family protein; Identified by similarity to SP:Q9RA63; match to protein family HMM PF07724.
 
   
0.850
MXAN_4824
ClpA/B family protein; Identified by similarity to SP:Q9RA63; match to protein family HMM PF07724.
 
   
0.850
MXAN_0113
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.769
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 
 0.733
clpP-2
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 
 0.731
MXAN_4268
Heat shock protein, HSP20 family; Identified by similarity to SP:Q06823; match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.
 
 
 0.660
MXAN_1092
Heat shock protein, HSP20 family; Identified by match to protein family HMM PF00011; Belongs to the small heat shock protein (HSP20) family.
 
 
 0.650
MXAN_2252
Putative arginine kinase; Identified by similarity to SP:P51541; Belongs to the ATP:guanido phosphotransferase family.
  
 
 0.643
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.639
MXAN_4717
Response regulator/DnaJ domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00226; match to protein family HMM PF07719.
  
 
 0.625
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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