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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_4852Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589; Belongs to the 'phage' integrase family. (334 aa)    
Predicted Functional Partners:
MXAN_1873
Site-specific recombinase, phage integrase family; Identified by match to protein family HMM PF00589.
 
 
 
 0.761
MXAN_1460
Identified by match to protein family HMM PF01580.
 
   
 0.604
topA
Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...]
 
  
 0.597
MXAN_4851
Transposase orfA, IS3 family; Identified by match to protein family HMM PF01527.
     
 0.581
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
   
 0.560
MXAN_5840
Prephenate dehydrogenase/chorismate mutase; Identified by match to protein family HMM PF01210; match to protein family HMM PF01817; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.
  
  
 0.560
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.557
MXAN_5161
Conserved hypothetical protein; Identified by similarity to GB:BAC90439.1; match to protein family HMM PF02586; Belongs to the SOS response-associated peptidase family.
   
  
 0.555
MXAN_1199
Competence protein F, truncated.
   
    0.523
MXAN_1235
ComF domain protein.
   
    0.523
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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