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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rtcRSigma-54 dependent transcriptional regulator RtcR; Identified by similarity to SP:P38035; match to protein family HMM PF00158; match to protein family HMM PF06956. (540 aa)    
Predicted Functional Partners:
rtcA-2
RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
  
 0.975
rtcA
RNA 3'-terminal phosphate cyclase; Identified by similarity to SP:P46849; match to protein family HMM PF01137; match to protein family HMM PF05189.
 
  
 0.953
MXAN_4982
Conserved hypothetical protein; Identified by similarity to PIR:C83072; match to protein family HMM PF01139.
 
   
 0.887
MXAN_0280
Conserved hypothetical protein; Identified by similarity to GB:BAC19645.1; match to protein family HMM PF01139.
 
   
 0.665
MXAN_1238
Conserved hypothetical protein; Identified by similarity to GB:AAN78862.1; match to protein family HMM PF01139.
 
   
 0.603
rtcB
Conserved hypothetical protein, UPF0027 family; Identified by match to protein family HMM PF01139; Belongs to the RtcB family.
 
   
 0.571
MXAN_1181
Conserved hypothetical protein; Identified by similarity to GB:CAD73061.1.
  
     0.564
rtcB-2
Conserved hypothetical protein; Identified by similarity to GB:AAQ59100.1; match to protein family HMM PF01139; Belongs to the RtcB family.
 
   
 0.499
MXAN_1184
Conserved hypothetical protein.
  
     0.448
MXAN_6657
Conserved hypothetical protein; Identified by match to protein family HMM PF06520.
 
     0.422
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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