STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_4987RNA polymerase sigma-70 factor, ECF subfamily; Identified by match to protein family HMM PF04542; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily. (200 aa)    
Predicted Functional Partners:
MXAN_4986
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.808
MXAN_4985
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
rpoE1
RNA polymerase sigma factor RpoE1; ECF subfamily; identified by similarity to GB:AAC98488.1; match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.539
MXAN_2184
RNA polymerase sigma-70 factor, ECF subfamily; Identified by match to protein family HMM PF04542; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family.
  
   
 0.510
MXAN_4988
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
       0.485
MXAN_4989
Hydrolase, alpha/beta fold family; Identified by match to protein family HMM PF00561.
       0.462
topA
Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...]
  
 
 0.408
MXAN_0233
RNA polymerase sigma-70 factor, group 3; Identified by match to protein family HMM PF04542; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
      
 0.404
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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