MXAN_5085 protein (Myxococcus xanthus) - STRING interaction network

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Score

MXAN_5085

Putative phosphomethylpyrimidine kinase. (246 aa)

Predicted Functional Partners:

thiE

0.998

MXAN_3267

0.990

thiC

0.980

thiD

0.928

thiG

0.818

MXAN_5086

0.782

MXAN_2228

0.743

thiS

0.684

MXAN_2588

0.671

MXAN_4069

0.570

Your Current Organism:

Myxococcus xanthus

NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MXAN_2228	MXAN_2588	MXAN_2228	MXAN_2588	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	0.533
MXAN_2228	MXAN_3267	MXAN_2228	MXAN_3267	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	Putative thiamine-phosphate pyrophosphorylase; Identified by match to protein family HMM PF02581.	0.566
MXAN_2228	MXAN_4069	MXAN_2228	MXAN_4069	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	ThiFdomain/MoeZ/MoeB domain protein; Identified by match to protein family HMM PF00899; match to protein family HMM PF05237.	0.490
MXAN_2228	MXAN_5085	MXAN_2228	MXAN_5085	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	Putative phosphomethylpyrimidine kinase.	0.743
MXAN_2228	thiC	MXAN_2228	MXAN_4235	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.667
MXAN_2228	thiD	MXAN_2228	MXAN_2287	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.	0.743
MXAN_2228	thiE	MXAN_2228	MXAN_5087	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.566
MXAN_2228	thiG	MXAN_2228	MXAN_3268	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.702
MXAN_2228	thiS	MXAN_2228	MXAN_3269	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.	0.621
MXAN_2588	MXAN_2228	MXAN_2588	MXAN_2228	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	0.533
MXAN_2588	MXAN_3267	MXAN_2588	MXAN_3267	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Putative thiamine-phosphate pyrophosphorylase; Identified by match to protein family HMM PF02581.	0.640
MXAN_2588	MXAN_5085	MXAN_2588	MXAN_5085	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Putative phosphomethylpyrimidine kinase.	0.671
MXAN_2588	thiC	MXAN_2588	MXAN_4235	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.783
MXAN_2588	thiD	MXAN_2588	MXAN_2287	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.	0.631
MXAN_2588	thiE	MXAN_2588	MXAN_5087	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.691
MXAN_2588	thiG	MXAN_2588	MXAN_3268	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.917
MXAN_2588	thiS	MXAN_2588	MXAN_3269	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.	0.790
MXAN_3267	MXAN_2228	MXAN_3267	MXAN_2228	Putative thiamine-phosphate pyrophosphorylase; Identified by match to protein family HMM PF02581.	Conserved hypothetical protein; Identified by similarity to GB:BAC59994.1.	0.566
MXAN_3267	MXAN_2588	MXAN_3267	MXAN_2588	Putative thiamine-phosphate pyrophosphorylase; Identified by match to protein family HMM PF02581.	rhodanese/MoeB/ThiF domain protein; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.	0.640
MXAN_3267	MXAN_4069	MXAN_3267	MXAN_4069	Putative thiamine-phosphate pyrophosphorylase; Identified by match to protein family HMM PF02581.	ThiFdomain/MoeZ/MoeB domain protein; Identified by match to protein family HMM PF00899; match to protein family HMM PF05237.	0.515