STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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nadKPutative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (305 aa)    
Predicted Functional Partners:
nadE
Putative glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.942
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.930
cobB
Sir2 family protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.
  
 
 0.916
cobB-2
NAD-dependent deacetylase; Identified by similarity to SP:P97013; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.916
sthA
NAD(P) transhydrogenase (B-specific); Identified by similarity to SP:P27306; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992.
   
 
 0.908
MXAN_4741
Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444.
     
 0.904
nudC
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293; Belongs to the Nudix hydrolase family. NudC subfamily.
     
 0.903
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.785
hsfA
DNA-binding reponse regulator HsfA; Identified by similarity to GB:AAK82998.1; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM TIGR01199.
       0.773
hsfB
Response regulator/sensor histidine kinase HsfB; Identified by similarity to GB:AAK82997.1; match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
       0.773
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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