STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MXAN_7454RNA polymerase sigma-70 factor, ECF subfamily; Identified by match to protein family HMM PF04542; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily. (212 aa)    
Predicted Functional Partners:
MXAN_7456
Conserved hypothetical protein; Identified by similarity to GB:AAL56580.1.
 
     0.886
MXAN_7455
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
MXAN_7458
FG-GAP repeat/fibronectin type III domain protein; Identified by match to protein family HMM PF00041; match to protein family HMM PF00396; match to protein family HMM PF01839.
   
   0.672
MXAN_7453
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.546
MXAN_7452
Hypothetical protein; Identified by Glimmer2; putative.
       0.544
MXAN_5545
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
  
     0.467
MXAN_1285
Tryptophan halogenase; Identified by match to protein family HMM PF01266; match to protein family HMM PF04820; match to protein family HMM PF07992.
  
    0.447
MXAN_1280
Identified by match to protein family HMM PF02518; match to protein family HMM PF06580.
  
     0.441
MXAN_7459
Putative methyltransferase; Identified by match to protein family HMM PF08123.
       0.440
topA
Putative DNA protecting protein DprA/DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the un [...]
  
 
 0.408
Your Current Organism:
Myxococcus xanthus
NCBI taxonomy Id: 246197
Other names: M. xanthus DK 1622, Myxococcus xanthus DK 1622
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