Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CUS_4274N-6 DNA Methylase; Identified by match to protein family HMM PF02384. (290 aa)    
Predicted Functional Partners:
CUS_4297
Hypothetical protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.
 
     0.976
CUS_4322
Hypothetical protein.
 
     0.976
CUS_4267
Hypothetical protein; Identified by glimmer; putative.
 
     0.962
CUS_4500
Type III restriction enzyme, res subunit; Identified by match to protein family HMM PF04851.
 
  
 0.858
CUS_5095
Type I restriction modification DNA specificity domain protein; Identified by match to protein family HMM PF01420.
 
 
 0.779
CUS_4334
Type I restriction modification DNA specificity domain protein; Identified by match to protein family HMM PF01420.
 
 
 0.705
CUS_5093
Hypothetical protein.
 
 
 0.701
CUS_5100
Type I restriction modification DNA specificity domain protein; Identified by match to protein family HMM PF01420.
 
 
 0.677
CUS_5097
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.596
CUS_4423
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.582
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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