Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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CUS_4413Histidinol phosphate phosphatase HisJ family; Identified by match to protein family HMM PF02811; match to protein family HMM TIGR01856; Belongs to the PHP hydrolase family. HisK subfamily. (258 aa)    
Predicted Functional Partners:
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475.
  
 
 0.812
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
 
 0.741
CUS_4414
Glycosyltransferase, group 2 family protein; Identified by match to protein family HMM PF00535.
       0.678
CUS_4415
Conserved domain protein.
       0.678
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.668
CUS_4416
Hypothetical protein.
       0.624
hisC
Histidinol-phosphate transaminase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.617
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
    0.471
CUS_4412
Putative 23S rRNA m2A2503 methyltransferase; Identified by match to protein family HMM PF04055; Belongs to the radical SAM superfamily. RlmN family.
  
    0.434
ybeY
Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
    0.421
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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