Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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pdxSPyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (290 aa)    
Predicted Functional Partners:
pdxT
Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
 0.999
pdxT-2
Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
 0.996
CUS_4511
Transcriptional regulator, GntR family; Identified by match to protein family HMM PF00392.
       0.702
CUS_6459
Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family.
    
 0.617
thiD
Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097.
    
 0.590
fsa
Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
    
  0.576
thrC
Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260.
   
    0.567
CUS_5794
Transketolase, thiamine pyrophosphate binding domain protein; Identified by match to protein family HMM PF00456.
    
  0.566
CUS_5795
Transketolase, pyridine binding domain protein; Identified by match to protein family HMM PF02779; match to protein family HMM PF02780.
    
  0.558
prs_1
Ribose-phosphate diphosphokinase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01251.
   
 
  0.558
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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