STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUS_4551Glycosyl hydrolase, family 31; Identified by match to protein family HMM PF01055; Belongs to the glycosyl hydrolase 31 family. (781 aa)    
Predicted Functional Partners:
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 
 0.897
CUS_7064
Hypothetical protein.
 
  
  0.884
CUS_7124
Glycosyl hydrolase family 3 C-terminal domain protein; Identified by match to protein family HMM PF00933; match to protein family HMM PF01915.
 
  
 0.864
cbg
Beta-glucosidase; Identified by match to protein family HMM PF00933; match to protein family HMM PF01915; Belongs to the glycosyl hydrolase 3 family.
 
  
 0.849
CUS_7348
Putative aconitate hydratase.
    
   0.841
CUS_7069
Alpha-galactosidase; Identified by match to protein family HMM PF02065.
 
  
 0.837
CUS_7631
Glycosyl hydrolase family 3 N-terminal domain protein; Identified by match to protein family HMM PF00933; match to protein family HMM PF01915; Belongs to the glycosyl hydrolase 3 family.
 
  
 0.824
CUS_4959
Alpha-galactosidase; Identified by match to protein family HMM PF02065.
 
  
 0.815
fba
Fructose-1,6-bisphosphate aldolase, class II; Identified by match to protein family HMM PF01116; match to protein family HMM TIGR00167; match to protein family HMM TIGR01859.
   
   0.813
CUS_6887
Alpha amylase, catalytic domain protein; Identified by match to protein family HMM PF00128.
  
 
 0.813
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.