CUS_4600 protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CUS_4600

Putative cyclase; Identified by match to protein family HMM PF04199. (192 aa)

Predicted Functional Partners:

CUS_4661

0.831

CUS_6560

0.728

CUS_6575

0.728

pckA

0.728

CUS_6888

0.728

CUS_7143

0.728

gcdB

0.728

ldh

0.666

cooF

0.666

pflB

0.557

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_4600	CUS_4661	CUS_4600	CUS_4661	Putative cyclase; Identified by match to protein family HMM PF04199.	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	0.831
CUS_4600	CUS_6560	CUS_4600	CUS_6560	Putative cyclase; Identified by match to protein family HMM PF04199.	Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723.	0.728
CUS_4600	CUS_6575	CUS_4600	CUS_6575	Putative cyclase; Identified by match to protein family HMM PF04199.	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	0.728
CUS_4600	CUS_6888	CUS_4600	CUS_6888	Putative cyclase; Identified by match to protein family HMM PF04199.	methylmalonyl-CoA carboxyltransferase 5S subunit; Identified by match to protein family HMM PF00682; match to protein family HMM PF02436.	0.728
CUS_4600	CUS_7143	CUS_4600	CUS_7143	Putative cyclase; Identified by match to protein family HMM PF04199.	Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; Identified by match to protein family HMM PF05681; match to protein family HMM TIGR00722.	0.728
CUS_4600	cooF	CUS_4600	CUS_7681	Putative cyclase; Identified by match to protein family HMM PF04199.	Identified by match to protein family HMM PF00037.	0.666
CUS_4600	gcdB	CUS_4600	CUS_7562	Putative cyclase; Identified by match to protein family HMM PF04199.	glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).	0.728
CUS_4600	ldh	CUS_4600	CUS_7535	Putative cyclase; Identified by match to protein family HMM PF04199.	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.	0.666
CUS_4600	pckA	CUS_4600	CUS_6871	Putative cyclase; Identified by match to protein family HMM PF04199.	Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.	0.728
CUS_4600	pflB	CUS_4600	CUS_4465	Putative cyclase; Identified by match to protein family HMM PF04199.	Formate C-acetyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02901; match to protein family HMM TIGR01255.	0.557
CUS_4661	CUS_4600	CUS_4661	CUS_4600	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	Putative cyclase; Identified by match to protein family HMM PF04199.	0.831
CUS_4661	CUS_6560	CUS_4661	CUS_6560	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	Hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723.	0.794
CUS_4661	CUS_6575	CUS_4661	CUS_6575	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	0.870
CUS_4661	CUS_6888	CUS_4661	CUS_6888	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	methylmalonyl-CoA carboxyltransferase 5S subunit; Identified by match to protein family HMM PF00682; match to protein family HMM PF02436.	0.794
CUS_4661	CUS_7143	CUS_4661	CUS_7143	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; Identified by match to protein family HMM PF05681; match to protein family HMM TIGR00722.	0.794
CUS_4661	cooF	CUS_4661	CUS_7681	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	Identified by match to protein family HMM PF00037.	0.976
CUS_4661	gcdB	CUS_4661	CUS_7562	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	glutaconyl-CoA decarboxylase subunit beta; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).	0.794
CUS_4661	ldh	CUS_4661	CUS_7535	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.	0.855
CUS_4661	pckA	CUS_4661	CUS_6871	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.	0.402
CUS_4661	pflB	CUS_4661	CUS_4465	Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.	Formate C-acetyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02901; match to protein family HMM TIGR01255.	0.823