Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iorAIndolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (577 aa)    
Predicted Functional Partners:
nifJ
Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
  
 0.972
CUS_4661
Ferredoxin hydrogenase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.
   
 0.938
CUS_4939
Indolepyruvate oxidoreductase subunit beta; Identified by match to protein family HMM PF01558.
 
 0.881
CUS_7232
Putative indolepyruvate ferredoxin oxidoreductase, beta subunit; Identified by match to protein family HMM PF01558.
 
 0.881
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
     
 0.832
CUS_4659
Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.
    
 0.755
hymB
Protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00037; match to protein family HMM PF01512.
    
 0.755
gltA
Glutamate synthase (NADPH), homotetrameric; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01316.
   
 0.748
CUS_7183
Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992.
   
 0.748
adhE
Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
   
 
 0.626
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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