Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_5062HD domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF01627; match to protein family HMM PF01966; match to protein family HMM PF08668. (492 aa)    
Predicted Functional Partners:
CUS_5106
Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 0.981
CUS_7923
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
 
 0.980
CUS_7748
Hypothetical protein.
 
 0.968
CUS_5287
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
 
 0.964
CUS_5104
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
 
0.947
CUS_7059
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00990; match to protein family HMM PF08495; match to protein family HMM TIGR00254.
 0.939
CUS_7759
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF02518.
 
 
 0.936
nifJ
Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
    
 0.933
ribA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.860
CUS_7982
Cyclic diguanylate phosphodiesterase (EAL) domain protein; Identified by match to protein family HMM PF00563.
 
 0.845
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
Server load: low (14%) [HD]