folE protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

folE

Putative GTP cyclohydrolase I; Identified by match to protein family HMM PF01227. (186 aa)

Predicted Functional Partners:

queD

0.994

queE

0.958

ribD

0.950

ribA

0.938

CUS_5104

0.896

CUS_5287

0.896

queF

0.875

queC

0.871

CUS_7748

0.867

CUS_5106

0.864

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_5104	CUS_5106	CUS_5104	CUS_5106	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	0.999
CUS_5104	CUS_5287	CUS_5104	CUS_5287	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	0.996
CUS_5104	CUS_7748	CUS_5104	CUS_7748	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	Hypothetical protein.	0.999
CUS_5104	folE	CUS_5104	CUS_5138	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	Putative GTP cyclohydrolase I; Identified by match to protein family HMM PF01227.	0.896
CUS_5104	ribA	CUS_5104	CUS_5649	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.920
CUS_5106	CUS_5104	CUS_5106	CUS_5104	Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	0.999
CUS_5106	CUS_5287	CUS_5106	CUS_5287	Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	0.999
CUS_5106	CUS_7748	CUS_5106	CUS_7748	Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Hypothetical protein.	0.997
CUS_5106	folE	CUS_5106	CUS_5138	Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	Putative GTP cyclohydrolase I; Identified by match to protein family HMM PF01227.	0.864
CUS_5106	ribA	CUS_5106	CUS_5649	Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.930
CUS_5287	CUS_5104	CUS_5287	CUS_5104	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	0.996
CUS_5287	CUS_5106	CUS_5287	CUS_5106	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	0.999
CUS_5287	CUS_7748	CUS_5287	CUS_7748	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	Hypothetical protein.	0.999
CUS_5287	folE	CUS_5287	CUS_5138	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	Putative GTP cyclohydrolase I; Identified by match to protein family HMM PF01227.	0.896
CUS_5287	ribA	CUS_5287	CUS_5649	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.920
CUS_7748	CUS_5104	CUS_7748	CUS_5104	Hypothetical protein.	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	0.999
CUS_7748	CUS_5106	CUS_7748	CUS_5106	Hypothetical protein.	Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.	0.997
CUS_7748	CUS_5287	CUS_7748	CUS_5287	Hypothetical protein.	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.	0.999
CUS_7748	folE	CUS_7748	CUS_5138	Hypothetical protein.	Putative GTP cyclohydrolase I; Identified by match to protein family HMM PF01227.	0.867
CUS_7748	ribA	CUS_7748	CUS_5649	Hypothetical protein.	GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.	0.935