Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_5153PASTA domain protein; Identified by match to protein family HMM PF03793. (1006 aa)    
Predicted Functional Partners:
CUS_7748
Hypothetical protein.
   
 0.921
CUS_6885
ABC-2 type transporter; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01061.
  
 
 0.899
CUS_6884
ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.
  
 
 0.898
CUS_4405
FHA domain protein; Identified by match to protein family HMM PF00498.
   
 
 0.849
CUS_5875
Clostripain family; Identified by match to protein family HMM PF03415.
   
 
 0.849
CUS_7179
Clostripain family; Identified by match to protein family HMM PF03415.
   
 
 0.849
CUS_5154
Sigma-70 region 2; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM PF08281; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
   
 
 0.825
CUS_5106
Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
   
 0.809
CUS_7923
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
   
 0.809
ribA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.769
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
Server load: low (26%) [HD]