CUS_5219 protein (Ruminococcus albus 8) - STRING interaction network

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CUS_5219

O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326. (432 aa)

Predicted Functional Partners:

metE

0.922

CUS_7787

0.910

CUS_6412

0.893

metK

0.864

cysK-3

0.856

luxS

0.851

CUS_7999

0.851

thrH

0.833

ilvA

0.817

cysK-2

0.765

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_5219	CUS_6412	CUS_5219	CUS_6412	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	0.893
CUS_5219	CUS_7787	CUS_5219	CUS_7787	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	0.910
CUS_5219	CUS_7999	CUS_5219	CUS_7999	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01326.	0.851
CUS_5219	cysK-2	CUS_5219	CUS_4907	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	0.765
CUS_5219	cysK-3	CUS_5219	CUS_6423	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.856
CUS_5219	ilvA	CUS_5219	CUS_6532	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.817
CUS_5219	luxS	CUS_5219	CUS_5595	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.	0.851
CUS_5219	metE	CUS_5219	CUS_4364	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.922
CUS_5219	metK	CUS_5219	CUS_8045	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.864
CUS_5219	thrH	CUS_5219	CUS_6866	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR02137.	0.833
CUS_6412	CUS_5219	CUS_6412	CUS_5219	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	0.893
CUS_6412	CUS_7787	CUS_6412	CUS_7787	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	0.963
CUS_6412	CUS_7999	CUS_6412	CUS_7999	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01326.	0.892
CUS_6412	ilvA	CUS_6412	CUS_6532	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.909
CUS_6412	luxS	CUS_6412	CUS_5595	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.	0.843
CUS_6412	metE	CUS_6412	CUS_4364	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.837
CUS_6412	thrH	CUS_6412	CUS_6866	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR02137.	0.889
CUS_7787	CUS_5219	CUS_7787	CUS_5219	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326.	0.910
CUS_7787	CUS_6412	CUS_7787	CUS_6412	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	0.963
CUS_7787	CUS_7999	CUS_7787	CUS_7999	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01053; match to protein family HMM TIGR01326.	0.910

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