metC protein (Ruminococcus albus 8) - STRING interaction network

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metC

Cystathionine beta-lyase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01053; match to protein family HMM PF01212. (385 aa)

Predicted Functional Partners:

mccA

0.985

CUS_7787

0.951

nifJ

0.934

cysK

0.915

cysK-2

0.915

cysK-3

0.915

metE

0.901

ilvA

0.894

metF

0.821

luxS

0.807

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_7787	cysK	CUS_7787	CUS_4694	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	0.812
CUS_7787	cysK-2	CUS_7787	CUS_4907	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	0.812
CUS_7787	cysK-3	CUS_7787	CUS_6423	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.855
CUS_7787	ilvA	CUS_7787	CUS_6532	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.955
CUS_7787	luxS	CUS_7787	CUS_5595	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.	0.940
CUS_7787	mccA	CUS_7787	CUS_5272	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	O-acetylserine dependent cystathionine beta-synthase; Identified by match to protein family HMM PF00291.	0.812
CUS_7787	metC	CUS_7787	CUS_5271	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Cystathionine beta-lyase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01053; match to protein family HMM PF01212.	0.951
CUS_7787	metE	CUS_7787	CUS_4364	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.983
CUS_7787	metF	CUS_7787	CUS_7369	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Methylenetetrahydrofolate reductase (NAD(P)H); Identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family.	0.999
CUS_7787	nifJ	CUS_7787	CUS_6517	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.	0.952
cysK	CUS_7787	CUS_4694	CUS_7787	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	0.812
cysK	ilvA	CUS_4694	CUS_6532	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.759
cysK	luxS	CUS_4694	CUS_5595	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.	0.686
cysK	metC	CUS_4694	CUS_5271	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	Cystathionine beta-lyase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01053; match to protein family HMM PF01212.	0.915
cysK	metE	CUS_4694	CUS_4364	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.642
cysK-2	CUS_7787	CUS_4907	CUS_7787	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	0.812
cysK-2	ilvA	CUS_4907	CUS_6532	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.759
cysK-2	luxS	CUS_4907	CUS_5595	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.	0.747
cysK-2	mccA	CUS_4907	CUS_5272	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	O-acetylserine dependent cystathionine beta-synthase; Identified by match to protein family HMM PF00291.	0.702
cysK-2	metC	CUS_4907	CUS_5271	Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139.	Cystathionine beta-lyase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01053; match to protein family HMM PF01212.	0.915