CUS_5406 protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CUS_5406

Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876. (96 aa)

Predicted Functional Partners:

radA

0.773

rplU

0.476

CUS_4791

0.465

CUS_5403

0.449

CUS_5569

0.447

CUS_6379

0.444

polA

0.436

CUS_5873

0.415

CUS_7748

0.414

rpmA

0.402

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_4791	CUS_5406	CUS_4791	CUS_5406	Conserved domain protein.	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	0.465
CUS_4791	CUS_5569	CUS_4791	CUS_5569	Conserved domain protein.	Hypothetical protein.	0.696
CUS_5403	CUS_5406	CUS_5403	CUS_5406	Identified by match to protein family HMM PF04327.	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	0.449
CUS_5403	radA	CUS_5403	CUS_5405	Identified by match to protein family HMM PF04327.	DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	0.449
CUS_5403	rplU	CUS_5403	CUS_5404	Identified by match to protein family HMM PF04327.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.986
CUS_5403	rpmA	CUS_5403	CUS_5402	Identified by match to protein family HMM PF04327.	Ribosomal protein L27; Identified by match to protein family HMM PF01016; match to protein family HMM TIGR00062; Belongs to the bacterial ribosomal protein bL27 family.	0.993
CUS_5406	CUS_4791	CUS_5406	CUS_4791	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	Conserved domain protein.	0.465
CUS_5406	CUS_5403	CUS_5406	CUS_5403	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	Identified by match to protein family HMM PF04327.	0.449
CUS_5406	CUS_5569	CUS_5406	CUS_5569	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	Hypothetical protein.	0.447
CUS_5406	CUS_5873	CUS_5406	CUS_5873	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993.	0.415
CUS_5406	CUS_6379	CUS_5406	CUS_6379	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	Hypothetical protein.	0.444
CUS_5406	CUS_7748	CUS_5406	CUS_7748	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	Hypothetical protein.	0.414
CUS_5406	polA	CUS_5406	CUS_6380	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.436
CUS_5406	radA	CUS_5406	CUS_5405	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.	0.773
CUS_5406	rplU	CUS_5406	CUS_5404	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.476
CUS_5406	rpmA	CUS_5406	CUS_5402	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	Ribosomal protein L27; Identified by match to protein family HMM PF01016; match to protein family HMM TIGR00062; Belongs to the bacterial ribosomal protein bL27 family.	0.402
CUS_5569	CUS_4791	CUS_5569	CUS_4791	Hypothetical protein.	Conserved domain protein.	0.696
CUS_5569	CUS_5406	CUS_5569	CUS_5406	Hypothetical protein.	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	0.447
CUS_5569	CUS_6379	CUS_5569	CUS_6379	Hypothetical protein.	Hypothetical protein.	0.696
CUS_5873	CUS_5406	CUS_5873	CUS_5406	NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993.	Stress responsive A/B barrel domain protein; Identified by match to protein family HMM PF07876.	0.415