| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUS_5452 | CUS_5453 | CUS_5452 | CUS_5453 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | DNA-binding helix-turn-helix protein; Identified by match to protein family HMM PF01381. | 0.405 |
| CUS_5452 | CUS_5811 | CUS_5452 | CUS_5811 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.576 |
| CUS_5452 | CUS_6238 | CUS_5452 | CUS_6238 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | Methyltransferase CheR, SAM binding domain protein; Identified by match to protein family HMM PF01739; match to protein family HMM PF03705. | 0.627 |
| CUS_5452 | CUS_6467 | CUS_5452 | CUS_6467 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | Conserved domain protein. | 0.427 |
| CUS_5452 | CUS_6468 | CUS_5452 | CUS_6468 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF01436; match to protein family HMM PF07719. | 0.402 |
| CUS_5452 | CUS_6471 | CUS_5452 | CUS_6471 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | ABC transporter, solute-binding protein; Identified by match to protein family HMM PF01547. | 0.478 |
| CUS_5452 | rpoA | CUS_5452 | CUS_6485 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | RNA polymerase, alpha subunit C-terminal domain protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.576 |
| CUS_5452 | rpoB | CUS_5452 | CUS_7658 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.659 |
| CUS_5452 | rpoC | CUS_5452 | CUS_7659 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.681 |
| CUS_5452 | topA | CUS_5452 | CUS_7449 | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.416 |
| CUS_5453 | CUS_5452 | CUS_5453 | CUS_5452 | DNA-binding helix-turn-helix protein; Identified by match to protein family HMM PF01381. | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | 0.405 |
| CUS_5811 | CUS_5452 | CUS_5811 | CUS_5452 | Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | 0.576 |
| CUS_5811 | rpoA | CUS_5811 | CUS_6485 | Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | RNA polymerase, alpha subunit C-terminal domain protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| CUS_5811 | rpoB | CUS_5811 | CUS_7658 | Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| CUS_5811 | rpoC | CUS_5811 | CUS_7659 | Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| CUS_5811 | topA | CUS_5811 | CUS_7449 | Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.478 |
| CUS_6238 | CUS_5452 | CUS_6238 | CUS_5452 | Methyltransferase CheR, SAM binding domain protein; Identified by match to protein family HMM PF01739; match to protein family HMM PF03705. | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | 0.627 |
| CUS_6467 | CUS_5452 | CUS_6467 | CUS_5452 | Conserved domain protein. | Sigma-70, region 4; Identified by match to protein family HMM PF04545; match to protein family HMM PF08281. | 0.427 |
| CUS_6467 | CUS_6468 | CUS_6467 | CUS_6468 | Conserved domain protein. | Tetratricopeptide repeat protein; Identified by match to protein family HMM PF00515; match to protein family HMM PF01436; match to protein family HMM PF07719. | 0.992 |
| CUS_6467 | CUS_6471 | CUS_6467 | CUS_6471 | Conserved domain protein. | ABC transporter, solute-binding protein; Identified by match to protein family HMM PF01547. | 0.897 |