STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUS_5467Transcriptional regulator, GntR family; Identified by match to protein family HMM PF00392. (364 aa)    
Predicted Functional Partners:
nifJ
Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
    
  0.783
CUS_5468
B3/4 domain protein; Identified by match to protein family HMM PF03483.
       0.714
CUS_7547
Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883.
 
  
 0.678
pdxS-2
Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
       0.643
pdxT-2
Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.637
CUS_5569
Hypothetical protein.
  
    0.540
CUS_5905
Transcriptional regulator, GntR family; Identified by match to protein family HMM PF00392.
  
    0.531
CUS_7916
Transcriptional regulator, GntR family; Identified by match to protein family HMM PF00392.
  
    0.513
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.509
nagA
N-acetylglucosamine-6-phosphate deacetylase; Identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221.
  
  
 0.454
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.