| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUS_5501 | CUS_5503 | CUS_5501 | CUS_5503 | Aminotransferase, class I/II; Identified by match to protein family HMM PF00155. | Efflux ABC transporter, permease protein; Identified by match to protein family HMM PF02687. | 0.432 |
| CUS_5501 | trpS | CUS_5501 | CUS_5502 | Aminotransferase, class I/II; Identified by match to protein family HMM PF00155. | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.714 |
| CUS_5503 | CUS_5501 | CUS_5503 | CUS_5501 | Efflux ABC transporter, permease protein; Identified by match to protein family HMM PF02687. | Aminotransferase, class I/II; Identified by match to protein family HMM PF00155. | 0.432 |
| CUS_5503 | guaA | CUS_5503 | CUS_6755 | Efflux ABC transporter, permease protein; Identified by match to protein family HMM PF02687. | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.565 |
| CUS_5503 | polA | CUS_5503 | CUS_6380 | Efflux ABC transporter, permease protein; Identified by match to protein family HMM PF02687. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.628 |
| CUS_5503 | trpS | CUS_5503 | CUS_5502 | Efflux ABC transporter, permease protein; Identified by match to protein family HMM PF02687. | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.618 |
| CUS_6918 | guaA | CUS_6918 | CUS_6755 | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.986 |
| CUS_6918 | ispH | CUS_6918 | CUS_7774 | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.668 |
| CUS_6918 | metG | CUS_6918 | CUS_6565 | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.910 |
| CUS_6918 | pheT | CUS_6918 | CUS_7019 | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. | phenylalanine--tRNA ligase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.976 |
| CUS_6918 | polA | CUS_6918 | CUS_6380 | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.630 |
| CUS_6918 | trpD | CUS_6918 | CUS_7846 | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.471 |
| CUS_6918 | trpS | CUS_6918 | CUS_5502 | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.736 |
| guaA | CUS_5503 | CUS_6755 | CUS_5503 | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | Efflux ABC transporter, permease protein; Identified by match to protein family HMM PF02687. | 0.565 |
| guaA | CUS_6918 | CUS_6755 | CUS_6918 | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857. | 0.986 |
| guaA | ispH | CUS_6755 | CUS_7774 | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.719 |
| guaA | metG | CUS_6755 | CUS_6565 | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.739 |
| guaA | pheT | CUS_6755 | CUS_7019 | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | phenylalanine--tRNA ligase, beta subunit; Identified by match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.897 |
| guaA | polA | CUS_6755 | CUS_6380 | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.790 |
| guaA | serS | CUS_6755 | CUS_5166 | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | serine--tRNA ligase; Identified by match to protein family HMM PF00587; match to protein family HMM PF02403; match to protein family HMM TIGR00414. | 0.535 |