| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUS_5106 | CUS_7748 | CUS_5106 | CUS_7748 | Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | Hypothetical protein. | 0.998 |
| CUS_5106 | CUS_7923 | CUS_5106 | CUS_7923 | Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | 0.997 |
| CUS_5106 | ilvA | CUS_5106 | CUS_6532 | Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.749 |
| CUS_5106 | luxS | CUS_5106 | CUS_5595 | Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.919 |
| CUS_5219 | CUS_7786 | CUS_5219 | CUS_7786 | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Vitamin B12 dependent methionine synthase, activation domain protein; Identified by match to protein family HMM PF02965. | 0.715 |
| CUS_5219 | CUS_7787 | CUS_5219 | CUS_7787 | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | 0.923 |
| CUS_5219 | cysK-3 | CUS_5219 | CUS_6423 | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Cysteine synthase A; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.909 |
| CUS_5219 | ilvA | CUS_5219 | CUS_6532 | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.791 |
| CUS_5219 | luxS | CUS_5219 | CUS_5595 | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.879 |
| CUS_5219 | metE | CUS_5219 | CUS_4364 | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.945 |
| CUS_7748 | CUS_5106 | CUS_7748 | CUS_5106 | Hypothetical protein. | Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | 0.998 |
| CUS_7748 | CUS_7923 | CUS_7748 | CUS_7923 | Hypothetical protein. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518. | 0.998 |
| CUS_7748 | ilvA | CUS_7748 | CUS_6532 | Hypothetical protein. | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.757 |
| CUS_7748 | luxS | CUS_7748 | CUS_5595 | Hypothetical protein. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.947 |
| CUS_7786 | CUS_5219 | CUS_7786 | CUS_5219 | Vitamin B12 dependent methionine synthase, activation domain protein; Identified by match to protein family HMM PF02965. | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | 0.715 |
| CUS_7786 | CUS_7787 | CUS_7786 | CUS_7787 | Vitamin B12 dependent methionine synthase, activation domain protein; Identified by match to protein family HMM PF02965. | Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | 0.988 |
| CUS_7786 | ilvA | CUS_7786 | CUS_6532 | Vitamin B12 dependent methionine synthase, activation domain protein; Identified by match to protein family HMM PF02965. | Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.822 |
| CUS_7786 | luxS | CUS_7786 | CUS_5595 | Vitamin B12 dependent methionine synthase, activation domain protein; Identified by match to protein family HMM PF02965. | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.870 |
| CUS_7786 | metE | CUS_7786 | CUS_4364 | Vitamin B12 dependent methionine synthase, activation domain protein; Identified by match to protein family HMM PF02965. | Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.682 |
| CUS_7787 | CUS_5219 | CUS_7787 | CUS_5219 | Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607. | O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; Identified by match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | 0.923 |