CUS_5808 protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CUS_5808

Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255. (305 aa)

Predicted Functional Partners:

gmk

0.927

CUS_5809

0.921

CUS_5811

0.840

priA

0.692

sun

0.684

fmt

0.678

def

0.647

CUS_5807

0.628

rlmN

0.543

CUS_5818

0.527

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_5807	CUS_5808	CUS_5807	CUS_5808	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	0.628
CUS_5807	CUS_5809	CUS_5807	CUS_5809	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	Identified by match to protein family HMM PF04025; Belongs to the RemA family.	0.538
CUS_5807	CUS_5811	CUS_5807	CUS_5811	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.509
CUS_5807	def	CUS_5807	CUS_5813	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.423
CUS_5807	fmt	CUS_5807	CUS_5814	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	0.422
CUS_5807	gmk	CUS_5807	CUS_5810	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.664
CUS_5807	priA	CUS_5807	CUS_5812	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.	0.440
CUS_5807	sun	CUS_5807	CUS_5815	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.408
CUS_5808	CUS_5807	CUS_5808	CUS_5807	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	0.628
CUS_5808	CUS_5809	CUS_5808	CUS_5809	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	Identified by match to protein family HMM PF04025; Belongs to the RemA family.	0.921
CUS_5808	CUS_5811	CUS_5808	CUS_5811	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.840
CUS_5808	CUS_5818	CUS_5808	CUS_5818	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	Putative serine/threonine-protein kinase PrkC; Identified by match to protein family HMM PF00069; match to protein family HMM PF01163; match to protein family HMM PF03793; match to protein family HMM PF07714.	0.527
CUS_5808	def	CUS_5808	CUS_5813	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.647
CUS_5808	fmt	CUS_5808	CUS_5814	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.	0.678
CUS_5808	gmk	CUS_5808	CUS_5810	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.927
CUS_5808	priA	CUS_5808	CUS_5812	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.	0.692
CUS_5808	rlmN	CUS_5808	CUS_5816	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.	0.543
CUS_5808	sun	CUS_5808	CUS_5815	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.	0.684
CUS_5809	CUS_5807	CUS_5809	CUS_5807	Identified by match to protein family HMM PF04025; Belongs to the RemA family.	HAD hydrolase, family IA, variant 1; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.	0.538
CUS_5809	CUS_5808	CUS_5809	CUS_5808	Identified by match to protein family HMM PF04025; Belongs to the RemA family.	Identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255.	0.921