STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUS_5953IMP cyclohydrolase-like protein. (238 aa)    
Predicted Functional Partners:
CUS_5948
AICARFT/IMPCHase bienzyme; Identified by match to protein family HMM PF01808.
 
  
 0.990
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
   
  0.961
CUS_6918
Phosphoribosylformylglycinamidine synthase; Identified by match to protein family HMM PF02769; match to protein family HMM TIGR01857.
  
 
 0.936
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.913
purD
Phosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM PF08442; match to protein family HMM TIGR00877; Belongs to the GARS family.
  
 
 0.684
CUS_5952
Hypothetical protein.
       0.651
CUS_5950
Identified by match to protein family HMM PF03691.
       0.580
CUS_5951
Hypothetical protein; Identified by glimmer; putative.
       0.580
CUS_4289
Hypothetical protein.
  
     0.560
CUS_5954
Hypothetical protein; Identified by glimmer; putative.
       0.553
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.