STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (411 aa)    
Predicted Functional Partners:
lspA
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.888
CUS_5977
Peptidase M16 inactive domain protein; Identified by match to protein family HMM PF05193; overlaps another CDS with the same product name.
 
    0.855
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.848
CUS_5978
Peptidase M16 inactive domain protein; Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; overlaps another CDS with the same product name.
  
    0.831
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.782
CUS_4979
Putative stage III sporulation protein J; Identified by match to protein family HMM PF02096; match to protein family HMM TIGR03592.
  
  
 0.710
folD
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
    0.685
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...]
  
  
 0.661
gpsA
Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Identified by match to protein family HMM PF01210; match to protein family HMM PF02558; match to protein family HMM PF03721; match to protein family HMM PF07479; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
    0.640
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
      
 0.625
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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