mgtE-2 protein (Ruminococcus albus 8) - STRING interaction network

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Score

mgtE-2

Magnesium transporter; Acts as a magnesium transporter. (481 aa)

Predicted Functional Partners:

guaA

0.906

CUS_6078

0.473

CUS_4678

0.471

purA

0.440

gmk

0.433

CUS_5948

0.421

rdgB

0.414

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_4678	CUS_5948	CUS_4678	CUS_5948	Hypothetical protein; Identified by glimmer; putative.	AICARFT/IMPCHase bienzyme; Identified by match to protein family HMM PF01808.	0.861
CUS_4678	gmk	CUS_4678	CUS_5810	Hypothetical protein; Identified by glimmer; putative.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.857
CUS_4678	guaA	CUS_4678	CUS_6755	Hypothetical protein; Identified by glimmer; putative.	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	0.922
CUS_4678	mgtE-2	CUS_4678	CUS_6079	Hypothetical protein; Identified by glimmer; putative.	Magnesium transporter; Acts as a magnesium transporter.	0.471
CUS_4678	purA	CUS_4678	CUS_7764	Hypothetical protein; Identified by glimmer; putative.	Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.892
CUS_4678	rdgB	CUS_4678	CUS_7437	Hypothetical protein; Identified by glimmer; putative.	Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.862
CUS_5948	CUS_4678	CUS_5948	CUS_4678	AICARFT/IMPCHase bienzyme; Identified by match to protein family HMM PF01808.	Hypothetical protein; Identified by glimmer; putative.	0.861
CUS_5948	guaA	CUS_5948	CUS_6755	AICARFT/IMPCHase bienzyme; Identified by match to protein family HMM PF01808.	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	0.922
CUS_5948	mgtE-2	CUS_5948	CUS_6079	AICARFT/IMPCHase bienzyme; Identified by match to protein family HMM PF01808.	Magnesium transporter; Acts as a magnesium transporter.	0.421
CUS_5948	purA	CUS_5948	CUS_7764	AICARFT/IMPCHase bienzyme; Identified by match to protein family HMM PF01808.	Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.974
CUS_5948	rdgB	CUS_5948	CUS_7437	AICARFT/IMPCHase bienzyme; Identified by match to protein family HMM PF01808.	Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.872
CUS_6078	mgtE-2	CUS_6078	CUS_6079	Hypothetical protein; Identified by glimmer; putative.	Magnesium transporter; Acts as a magnesium transporter.	0.473
gmk	CUS_4678	CUS_5810	CUS_4678	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Hypothetical protein; Identified by glimmer; putative.	0.857
gmk	guaA	CUS_5810	CUS_6755	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	0.978
gmk	mgtE-2	CUS_5810	CUS_6079	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Magnesium transporter; Acts as a magnesium transporter.	0.433
gmk	purA	CUS_5810	CUS_7764	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.418
guaA	CUS_4678	CUS_6755	CUS_4678	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Hypothetical protein; Identified by glimmer; putative.	0.922
guaA	CUS_5948	CUS_6755	CUS_5948	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	AICARFT/IMPCHase bienzyme; Identified by match to protein family HMM PF01808.	0.922
guaA	gmk	CUS_6755	CUS_5810	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.978
guaA	mgtE-2	CUS_6755	CUS_6079	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Magnesium transporter; Acts as a magnesium transporter.	0.906