Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CUS_6086Transporter, major facilitator family protein; Identified by match to protein family HMM PF07690. (466 aa)    
Predicted Functional Partners:
CUS_6085
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
 
     0.892
CUS_5429
FMN-binding domain protein; Identified by match to protein family HMM PF00041; match to protein family HMM PF04205; match to protein family HMM PF07581.
  
     0.509
maf
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    
  0.508
CUS_7029
Glycosyl hydrolase, family 43; Identified by match to protein family HMM PF04616; Belongs to the glycosyl hydrolase 43 family.
  
  
 0.508
CUS_4678
Hypothetical protein; Identified by glimmer; putative.
   
 
 0.505
CUS_4944
GHMP kinase, N-terminal domain protein; Identified by match to protein family HMM PF00288; Belongs to the GHMP kinase family.
  
  
 0.499
CUS_4594
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
  
     0.493
thyX
Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
     
  0.492
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
     
  0.492
CUS_7826
dTMP kinase; Identified by match to protein family HMM PF02223.
     
 0.445
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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