STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigKRNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (231 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.871
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.869
spoIVB
SpoIVB peptidase; Identified by match to protein family HMM PF05580; match to protein family HMM TIGR02860.
  
  
 0.852
CUS_5685
Sporulation initiation factor Spo0A C-terminal domain protein; Identified by match to protein family HMM PF08769.
  
  
 0.835
rpoA
RNA polymerase, alpha subunit C-terminal domain protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.826
CUS_4878
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.814
gpr
Putative GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
    0.810
CUS_5966
Putative stage II sporulation protein E; Identified by match to protein family HMM PF07228.
  
  
 0.807
spoIVA
Stage IV sporulation protein A; Identified by match to protein family HMM PF09547; match to protein family HMM TIGR02836.
  
   
 0.792
spoVAD
Stage V sporulation protein AD; Identified by match to protein family HMM PF07451.
 
    0.790
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.