Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_6274Methyltransferase domain protein; Identified by match to protein family HMM PF00248; match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242. (526 aa)    
Predicted Functional Partners:
CUS_5202
Oxidoreductase, aldo/keto reductase family protein; Identified by match to protein family HMM PF00248.
 
     0.674
thiD
Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097.
    
 0.671
CUS_7642
Putative glucokinase; Identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744.
  
  
  0.667
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
     
  0.666
CUS_6459
Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family.
   
 
  0.666
CUS_6273
Hypothetical protein; Identified by glimmer; putative.
       0.543
CUS_5848
Putative glycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.422
adhE
Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.421
adhE-2
Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.421
CUS_5646
AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.
  
 0.413
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
Server load: low (8%) [HD]