| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUS_5787 | CUS_6459 | CUS_5787 | CUS_6459 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | 0.642 |
| CUS_6274 | CUS_6459 | CUS_6274 | CUS_6459 | Methyltransferase domain protein; Identified by match to protein family HMM PF00248; match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242. | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | 0.666 |
| CUS_6274 | thiD | CUS_6274 | CUS_6957 | Methyltransferase domain protein; Identified by match to protein family HMM PF00248; match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242. | Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097. | 0.671 |
| CUS_6453 | CUS_6458 | CUS_6453 | CUS_6458 | EDD domain protein, DegV family; Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762. | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | 0.532 |
| CUS_6453 | CUS_6459 | CUS_6453 | CUS_6459 | EDD domain protein, DegV family; Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762. | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | 0.547 |
| CUS_6458 | CUS_6453 | CUS_6458 | CUS_6453 | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | EDD domain protein, DegV family; Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762. | 0.532 |
| CUS_6458 | CUS_6459 | CUS_6458 | CUS_6459 | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | 0.782 |
| CUS_6459 | CUS_5787 | CUS_6459 | CUS_5787 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.642 |
| CUS_6459 | CUS_6274 | CUS_6459 | CUS_6274 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | Methyltransferase domain protein; Identified by match to protein family HMM PF00248; match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242. | 0.666 |
| CUS_6459 | CUS_6453 | CUS_6459 | CUS_6453 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | EDD domain protein, DegV family; Identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762. | 0.547 |
| CUS_6459 | CUS_6458 | CUS_6459 | CUS_6458 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | 0.782 |
| CUS_6459 | CUS_7836 | CUS_6459 | CUS_7836 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243. | 0.846 |
| CUS_6459 | pdxS | CUS_6459 | CUS_4513 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.617 |
| CUS_6459 | pdxS-2 | CUS_6459 | CUS_5465 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.617 |
| CUS_6459 | pdxT | CUS_6459 | CUS_4512 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.589 |
| CUS_6459 | pdxT-2 | CUS_6459 | CUS_5466 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.589 |
| CUS_6459 | thiD | CUS_6459 | CUS_6957 | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097. | 0.715 |
| CUS_7836 | CUS_6459 | CUS_7836 | CUS_6459 | Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243. | Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family. | 0.846 |
| CUS_7836 | pdxS | CUS_7836 | CUS_4513 | Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243. | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.557 |
| CUS_7836 | pdxS-2 | CUS_7836 | CUS_5465 | Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243. | Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.557 |