CUS_6536 protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CUS_6536

Transporter, CPA2 family; Identified by match to protein family HMM PF00999. (397 aa)

Predicted Functional Partners:

CUS_6535

0.451

CUS_5997

0.418

ilvA

0.414

guaA

0.413

CUS_4390

0.412

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_4390	CUS_6536	CUS_4390	CUS_6536	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	0.412
CUS_5997	CUS_6536	CUS_5997	CUS_6536	Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	0.418
CUS_5997	guaA	CUS_5997	CUS_6755	Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	0.695
CUS_6535	CUS_6536	CUS_6535	CUS_6536	Putative endoribonuclease L-PSP; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004.	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	0.451
CUS_6535	guaA	CUS_6535	CUS_6755	Putative endoribonuclease L-PSP; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004.	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	0.596
CUS_6535	ilvA	CUS_6535	CUS_6532	Putative endoribonuclease L-PSP; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.810
CUS_6536	CUS_4390	CUS_6536	CUS_4390	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	0.412
CUS_6536	CUS_5997	CUS_6536	CUS_5997	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.	0.418
CUS_6536	CUS_6535	CUS_6536	CUS_6535	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	Putative endoribonuclease L-PSP; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004.	0.451
CUS_6536	guaA	CUS_6536	CUS_6755	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	0.413
CUS_6536	ilvA	CUS_6536	CUS_6532	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.414
guaA	CUS_5997	CUS_6755	CUS_5997	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.	0.695
guaA	CUS_6535	CUS_6755	CUS_6535	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Putative endoribonuclease L-PSP; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004.	0.596
guaA	CUS_6536	CUS_6755	CUS_6536	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	0.413
guaA	ilvA	CUS_6755	CUS_6532	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.635
ilvA	CUS_6535	CUS_6532	CUS_6535	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	Putative endoribonuclease L-PSP; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004.	0.810
ilvA	CUS_6536	CUS_6532	CUS_6536	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	Transporter, CPA2 family; Identified by match to protein family HMM PF00999.	0.414
ilvA	guaA	CUS_6532	CUS_6755	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	0.635