| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUS_5788 | CUS_6548 | CUS_5788 | CUS_6548 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | 0.593 |
| CUS_5788 | CUS_6552 | CUS_5788 | CUS_6552 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | Putative cell division protein FtsW; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | 0.461 |
| CUS_5788 | ftsZ | CUS_5788 | CUS_6558 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.955 |
| CUS_5788 | mraW | CUS_5788 | CUS_6546 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.493 |
| CUS_5788 | mraZ | CUS_5788 | CUS_6545 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | Protein MraZ; Identified by match to protein family HMM PF02381; match to protein family HMM TIGR00242; Belongs to the MraZ family. | 0.528 |
| CUS_5788 | murD | CUS_5788 | CUS_8035 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.460 |
| CUS_5788 | murE | CUS_5788 | CUS_6549 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.506 |
| CUS_5788 | murF | CUS_5788 | CUS_6550 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.491 |
| CUS_6547 | CUS_6548 | CUS_6547 | CUS_6548 | Putative cell division protein FtsL. | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | 0.536 |
| CUS_6547 | mraW | CUS_6547 | CUS_6546 | Putative cell division protein FtsL. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.621 |
| CUS_6547 | mraZ | CUS_6547 | CUS_6545 | Putative cell division protein FtsL. | Protein MraZ; Identified by match to protein family HMM PF02381; match to protein family HMM TIGR00242; Belongs to the MraZ family. | 0.599 |
| CUS_6548 | CUS_5788 | CUS_6548 | CUS_5788 | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.593 |
| CUS_6548 | CUS_6547 | CUS_6548 | CUS_6547 | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | Putative cell division protein FtsL. | 0.536 |
| CUS_6548 | CUS_6552 | CUS_6548 | CUS_6552 | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | Putative cell division protein FtsW; Identified by match to protein family HMM PF01098; Belongs to the SEDS family. | 0.995 |
| CUS_6548 | CUS_7768 | CUS_6548 | CUS_7768 | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | Putative stage III sporulation protein E; Identified by match to protein family HMM PF01580; match to protein family HMM PF09397; Belongs to the FtsK/SpoIIIE/SftA family. | 0.742 |
| CUS_6548 | ftsZ | CUS_6548 | CUS_6558 | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.503 |
| CUS_6548 | mraW | CUS_6548 | CUS_6546 | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.774 |
| CUS_6548 | mraZ | CUS_6548 | CUS_6545 | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | Protein MraZ; Identified by match to protein family HMM PF02381; match to protein family HMM TIGR00242; Belongs to the MraZ family. | 0.765 |
| CUS_6548 | murD | CUS_6548 | CUS_8035 | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.897 |
| CUS_6548 | murE | CUS_6548 | CUS_6549 | Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.961 |