Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_67448-oxoguanine DNA-glycosylase (ogg). (271 aa)    
Predicted Functional Partners:
xth
Exodeoxyribonuclease III; Identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633.
   
 0.845
CUS_6745
Conserved domain protein.
       0.773
CUS_7430
Identified by match to protein family HMM PF01261.
    
 
 0.733
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.655
CUS_4456
Hypothetical protein.
    
 0.617
CUS_6746
Hypothetical protein.
       0.616
CUS_4921
DNA replication protein DnaC family protein.
  
     0.597
CUS_8148
Cof-like hydrolase; Identified by match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484.
      0.538
CUS_4920
DnaD domain protein; Identified by match to protein family HMM PF04271; match to protein family HMM TIGR01446.
  
     0.531
CUS_6743
Conserved domain protein.
       0.461
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
Server load: low (26%) [HD]