Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651.
 
 
 0.999
nifJ
Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
 
  
 0.967
CUS_5922
AMP-binding enzyme; Identified by match to protein family HMM PF00501.
     
 0.947
adhE
Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.905
adhE-2
Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.905
CUS_7366
Acylphosphatase; Identified by match to protein family HMM PF00708.
     
 0.853
xfp
D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; Identified by match to protein family HMM PF03894; match to protein family HMM PF09363; match to protein family HMM PF09364.
  
 0.750
CUS_8015
Citrate (Si)-synthase; Identified by match to protein family HMM PF00285.
   
 
 0.733
CUS_5867
Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.
     
 0.713
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
     
 0.704
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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