STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dprADNA protecting protein DprA; Identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732. (288 aa)    
Predicted Functional Partners:
CUS_7657
Mg chelatase-like protein; Identified by match to protein family HMM PF01078; match to protein family HMM PF07728; match to protein family HMM TIGR00368.
 
 0.813
CUS_7707
Identified by match to protein family HMM PF00156.
 
 
 0.811
CUS_4913
Identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360.
 
  
 0.750
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.710
CUS_7957
Bacterial peptidase A24, N-terminal domain protein; Identified by match to protein family HMM PF01478; match to protein family HMM PF06750.
 
  
 0.652
CUS_5104
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
  
    0.634
CUS_5287
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
  
    0.634
CUS_7059
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00990; match to protein family HMM PF08495; match to protein family HMM TIGR00254.
   
    0.612
CUS_5517
Peptidase, A24 family; Identified by match to protein family HMM PF01478.
  
  
 0.606
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.589
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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