CUS_6941 protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CUS_6941

Conserved domain protein. (287 aa)

Predicted Functional Partners:

CUS_5646

0.842

htpG

0.791

cysS

0.786

CUS_4387

0.765

rplQ

0.758

rplN

0.748

dnaJ

0.736

rplU

0.730

rplK

0.730

rplO

0.727

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_4387	CUS_5646	CUS_4387	CUS_5646	WD domain, G-beta repeat protein.	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	0.583
CUS_4387	CUS_6941	CUS_4387	CUS_6941	WD domain, G-beta repeat protein.	Conserved domain protein.	0.765
CUS_4387	dnaJ	CUS_4387	CUS_6701	WD domain, G-beta repeat protein.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.818
CUS_4387	rplK	CUS_4387	CUS_8154	WD domain, G-beta repeat protein.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.782
CUS_4387	rplN	CUS_4387	CUS_6504	WD domain, G-beta repeat protein.	Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.796
CUS_4387	rplO	CUS_4387	CUS_6495	WD domain, G-beta repeat protein.	Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.750
CUS_5646	CUS_4387	CUS_5646	CUS_4387	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	WD domain, G-beta repeat protein.	0.583
CUS_5646	CUS_6941	CUS_5646	CUS_6941	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	Conserved domain protein.	0.842
CUS_5646	dnaJ	CUS_5646	CUS_6701	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.879
CUS_5646	htpG	CUS_5646	CUS_6236	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.	0.452
CUS_5646	rplK	CUS_5646	CUS_8154	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.632
CUS_5646	rplN	CUS_5646	CUS_6504	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.650
CUS_5646	rplO	CUS_5646	CUS_6495	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.778
CUS_5646	rplQ	CUS_5646	CUS_6484	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	Ribosomal protein L17; Identified by match to protein family HMM PF01196.	0.625
CUS_5646	rplU	CUS_5646	CUS_5404	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.633
CUS_6941	CUS_4387	CUS_6941	CUS_4387	Conserved domain protein.	WD domain, G-beta repeat protein.	0.765
CUS_6941	CUS_5646	CUS_6941	CUS_5646	Conserved domain protein.	AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.	0.842
CUS_6941	cysS	CUS_6941	CUS_6940	Conserved domain protein.	cysteine--tRNA ligase; Identified by match to protein family HMM PF01406; match to protein family HMM PF09190; match to protein family HMM PF09334; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.786
CUS_6941	dnaJ	CUS_6941	CUS_6701	Conserved domain protein.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.736
CUS_6941	htpG	CUS_6941	CUS_6236	Conserved domain protein.	Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.	0.791