thiD protein (Ruminococcus albus 8) - STRING interaction network

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thiD

Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097. (269 aa)

Predicted Functional Partners:

thiE

0.999

thiC

0.999

thiG

0.961

thiS

0.949

thiH

0.880

CUS_5657

0.810

guaA

0.778

thiI

0.755

CUS_5997

0.724

CUS_6459

0.715

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_5657	CUS_5997	CUS_5657	CUS_5997	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.	0.438
CUS_5657	guaA	CUS_5657	CUS_6755	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	0.695
CUS_5657	thiC	CUS_5657	CUS_6958	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.	0.825
CUS_5657	thiD	CUS_5657	CUS_6957	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097.	0.810
CUS_5657	thiE	CUS_5657	CUS_6956	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.856
CUS_5657	thiG	CUS_5657	CUS_6954	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.992
CUS_5657	thiH	CUS_5657	CUS_6955	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	Thiazole biosynthesis protein ThiH; Identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR02351.	0.725
CUS_5657	thiI	CUS_5657	CUS_6255	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.	0.911
CUS_5657	thiS	CUS_5657	CUS_6952	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.	0.986
CUS_5997	CUS_5657	CUS_5997	CUS_5657	Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	0.438
CUS_5997	guaA	CUS_5997	CUS_6755	Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	0.852
CUS_5997	thiD	CUS_5997	CUS_6957	Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.	Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097.	0.724
CUS_6459	thiD	CUS_6459	CUS_6957	Putative pyridoxal kinase; Identified by match to protein family HMM PF08543; Belongs to the pyridoxine kinase family.	Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097.	0.715
guaA	CUS_5657	CUS_6755	CUS_5657	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	0.695
guaA	CUS_5997	CUS_6755	CUS_5997	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.	0.852
guaA	thiD	CUS_6755	CUS_6957	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097.	0.778
guaA	thiG	CUS_6755	CUS_6954	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.528
guaA	thiH	CUS_6755	CUS_6955	GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.	Thiazole biosynthesis protein ThiH; Identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR02351.	0.402
thiC	CUS_5657	CUS_6958	CUS_5657	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.	Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237; overlaps another CDS with the same product name.	0.825
thiC	thiD	CUS_6958	CUS_6957	Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.	Phosphomethylpyrimidine kinase; Identified by match to protein family HMM PF08543; match to protein family HMM TIGR00097.	0.999