Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_6988ADP-ribosylglycohydrolase; Identified by match to protein family HMM PF03747. (311 aa)    
Predicted Functional Partners:
CUS_7487
Macro domain protein; Identified by match to protein family HMM PF01661.
   
 0.821
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
       0.773
rseP
RIP metalloprotease RseP; Identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054.
       0.773
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.755
polC
DNA polymerase III, alpha subunit, Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
       0.693
CUS_5997
Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; match to protein family HMM PF00909; match to protein family HMM TIGR00836; Belongs to the P(II) protein family.
   
 
 0.637
CUS_6991
Hypothetical protein; Identified by glimmer; putative.
       0.627
uppS
Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
       0.572
cdsA
Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF01148.
       0.572
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
       0.568
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.