Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_7121ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (455 aa)    
Predicted Functional Partners:
CUS_7120
Putative heme response regulator HssR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
  0.969
CUS_7748
Hypothetical protein.
  
 0.958
CUS_5104
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
  
 0.942
CUS_5287
Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254.
  
 0.942
CUS_4848
Putative transcriptional regulatory protein ResD; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
  0.866
CUS_7744
Response regulator receiver domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00072.
 
  0.863
CUS_5425
Putative subtilin biosynthesis regulatory protein SpaR; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
  0.840
CUS_7543
Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
  
 0.836
CUS_7750
Putative sensory transduction protein RegX3; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
  
 0.834
CUS_6964
Response regulator receiver domain protein; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
  
  0.831
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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