STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pncBNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (479 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.941
CUS_8051
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.916
CUS_6254
Competence/damage-inducible protein CinA C-terminal domain protein; Identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199; Belongs to the CinA family.
  
 
 0.907
CUS_6797
Isochorismatase family protein.
  
 
 0.904
nadC
Nicotinate-nucleotide diphosphorylase (carboxylating); Identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family.
   
 0.857
CUS_5986
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
    
 0.776
CUS_4626
Hydrolase, HD family; Identified by match to protein family HMM PF01966; match to protein family HMM TIGR00277; match to protein family HMM TIGR00488.
     
 0.760
CUS_6289
Putative L-aspartate oxidase; Identified by match to protein family HMM PF00890.
     
 0.756
CUS_4678
Hypothetical protein; Identified by glimmer; putative.
    
 0.746
CUS_4675
SH3 domain protein; Identified by match to protein family HMM PF01551; match to protein family HMM PF08239.
    
  0.729
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.